Drug Profile


Alternative Names: MK-1439; MK-1439-019

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Merck & Co
  • Class Antiretrovirals; Nitriles; Pyridones; Small molecules; Triazoles
  • Mechanism of Action Non-nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HIV-1 infections

Most Recent Events

  • 09 Nov 2017 National Institute of Allergy and Infectious Diseases plans a phase I/II trial for HIV-1 infections (In children, In adolescents) in USA, South Africa and Thailand in March 2018 (NCT03332095)
  • 28 Feb 2017 Merck has patent protection for doravirine in USA (Merck Annual report 2016)
  • 28 Feb 2017 Positive 48-week efficacy data from a phase III trial in HIV-1 infections released by Merck (2016 Merck Annual report)
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