VXM 01

Drug Profile

VXM 01

Alternative Names: VEGFR2 peptide vaccine - VAXIMM; VEGFR2 specific T cell vaccine - VAXIMM; VXM-01

Latest Information Update: 15 Sep 2017

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At a glance

  • Originator Merck KGaA
  • Developer VAXIMM
  • Class Cancer vaccines; DNA vaccines; Peptide vaccines
  • Mechanism of Action Angiogenesis inhibitors; Immunostimulants; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Phase I Colorectal cancer; Glioblastoma; Pancreatic cancer
  • Preclinical Solid tumours

Most Recent Events

  • 13 Sep 2017 VXM 01 receives Orphan Drug status for Glioma in European Union
  • 13 Sep 2017 VXM 01 receives Orphan Drug status for Glioma in USA
  • 03 Jun 2017 Interim adverse events, efficacy and immunogenicity data from the phase I trial in Glioblastoma (Late-stage disease, Recurrent, Second-line therapy or greater) presented at the 53rd annual meeting of the American Society of Clinical Oncology (ASCO-2017)
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