Drug Profile


Alternative Names: CTX-4430; EP-501

Latest Information Update: 09 Jun 2017

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At a glance

  • Originator Unknown
  • Developer Celtaxsys
  • Class Small molecules
  • Mechanism of Action Leukotriene A4 hydrolase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acne vulgaris; Cystic fibrosis
  • Phase I Hidradenitis suppurativa
  • Preclinical Rosacea

Most Recent Events

  • 09 Jun 2017 Chemical structure information added
  • 18 May 2017 Celtaxsys completes enrolment in the EMPIRE-CF phase IIb trial for Cystic fibrosis in Belgium, Canada, France, Germany, Italy, United Kingdom and USA
  • 09 Jan 2017 Phase-II clinical trials in Cystic fibrosis in Canada (PO) before January 2017
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