AKB 4924

Drug Profile

AKB 4924

Alternative Names: AKB-4924

Latest Information Update: 29 Mar 2017

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At a glance

  • Originator Procter & Gamble
  • Developer Aerpio Pharmaceuticals
  • Class Anti-inflammatories; Piperazines; Pyridones; Small molecules
  • Mechanism of Action EGLN2 protein inhibitors; Hypoxia inducible factor 1 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Inflammatory bowel diseases

Most Recent Events

  • 15 Mar 2017 Zeta Acquisition Corp II in a reverse merger transaction acquires Aerpio Therapeutics and changes its name to Aerpio Pharmaceuticals
  • 01 Jan 2017 Aerpio Therapeutics completes a phase I trial in Healthy volunteers in Canada (NCT02914262)
  • 01 Aug 2016 Phase-I clinical trials in Inflammatory bowel disease (In volunteers) in Canada (PO) (NCT02914262)
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