Drug Profile


Alternative Names: DE 126; ONO 9054

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Ono Pharmaceutical
  • Class Eye disorder therapies
  • Mechanism of Action Prostaglandin E EP3 receptor agonists; Prostaglandin F2 alpha agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ocular hypertension; Open-angle glaucoma

Most Recent Events

  • 08 Aug 2017 Chemical structure information added
  • 25 Jul 2017 Santen initiates the phase IIb Angel trial for Open angle glaucoma and Ocular hypertension in USA (NCT03216902)
  • 11 Jul 2017 Santen plans a phase IIb trial (Angel study) for Open angle glaucoma and Ocular hypertension in USA in July 2017 (NCT03216902)
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