Drug Profile


Alternative Names: IDX-18719; IDX-719; MK-1894

Latest Information Update: 02 Jun 2015

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At a glance

  • Originator Idenix Pharmaceuticals
  • Developer Janssen Pharmaceuticals; Merck & Co
  • Class Antivirals; Benzimidazoles; Carbamates; Imidazoles; Pyrrolidines; Thiophenes
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis C

Most Recent Events

  • 01 Apr 2015 Merck and Janssen complete the phase II HELIX-1 trial in Hepatitis C (Combination therapy, Treatment-naive) in USA (NCT01852604)
  • 20 Feb 2015 Discontinued - Phase-I/II for Hepatitis C in USA (PO) (Merck & Co, pipeline, February 2015)
  • 20 Feb 2015 Discontinued - Phase-II for Hepatitis C (Combination therapy, Treatment-naive) in USA (PO) (Merck & Co, pipeline, February 2015)
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