Huperzine A - Biscayne Pharmaceuticals

Drug Profile

Huperzine A - Biscayne Pharmaceuticals

Alternative Names: BIS-001; BIS-001ER; INS-001

Latest Information Update: 03 Nov 2017

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At a glance

  • Originator Harvard University
  • Developer Biscayne Pharmaceuticals
  • Class Alkaloids; Neuroprotectants; Nootropics; Sesquiterpenes
  • Mechanism of Action Acetylcholinesterase inhibitors; NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Dravet syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Epilepsy

Most Recent Events

  • 19 Oct 2017 Biscayne Neurotherapeutics plans a phase IIa trial for extended release formulation of huperzine A for Seizures in early 2018 (Trial profile 700281277)
  • 22 May 2017 Phase-I clinical trials in Epilepsy (In volunteers) in Australia (unspecified route) (NCT03156439)
  • 09 May 2017 Australian regulatory authority approves clinical trial application for a phase Ib trial of Huperzine A in Epilepsy
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