PVX 410

Drug Profile

PVX 410

Alternative Names: PVX-410; XBP1-US/XBP1-SP/CD138/CS1 multipeptide vaccine PVX-410

Latest Information Update: 03 Feb 2017

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At a glance

  • Originator Dana-Farber Cancer Institute
  • Developer AstraZeneca; Emory University; Massachusetts General Hospital; OncoPep
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Multiple myeloma
  • Phase I Breast cancer

Most Recent Events

  • 03 Feb 2017 Adverse events and immunogenicity data from a phase I/IIa trial in Multiple myeloma presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2016)
  • 28 Nov 2016 Immunogenicity and safety data from a phase I/IIa trial in Multiple myeloma released by OncoPep
  • 28 Nov 2016 OncoPep, Celgene and Massachusetts General Hospital initiate a phase Ib trial for Multiple Myeloma (Combination therapy) in USA (NCT02886065)
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