Research programme: targeted cancer therapeutics - Intrexon/ZIOPHARM

Drug Profile

Research programme: targeted cancer therapeutics - Intrexon/ZIOPHARM

Alternative Names: ACT-based immunotherapy - Intrexon/ZIOPHARM; Adoptive cell transfer-based immunotherapy - Intrexon/ZIOPHARM; Anti-CD3-anti-EGFR CLM - Intrexon/ZIOPHARM; CAR-T cell therapeutics - Intrexon/ZIOPHARM/Merck Serono; Cell linking moieties - Intrexon/ZIOPHARM; Cetux-CAR T cells - Intrexon/ZIOPHARM; CLM expressing allogeneic cell therapeutics - Intrexon/ZIOPHARM; ERC-RTS-CLM; Natural killer cells - Ziopharm; Nimo-CAR T cells - Intrexon/ZIOPHARM; NK cells - Ziopharm; Non-viral adoptive cellular cancer immunotherapies - Intrexon/ZIOPHARM; pRTS-IFNα; RTS-IFNα

Latest Information Update: 02 Mar 2017

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At a glance

  • Originator Intrexon Corporation; ZIOPHARM Oncology
  • Developer Intrexon Corporation; Merck Serono; University of Texas M. D. Anderson Cancer Center; ZIOPHARM Oncology
  • Class Bispecific antibodies; CAR-T cell therapies; Cell therapies; Gene therapies
  • Mechanism of Action Apoptosis stimulants; Gene expression modulators; Gene transference; Immunostimulants; Interleukin 12 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Brain cancer; Cancer
  • Research Non-small cell lung cancer

Most Recent Events

  • 01 May 2017 Ziopharm plans a phase I trial for Acute myeloid leukaemia
  • 16 Feb 2017 Preclinical development is ongoing in USA
  • 10 Jan 2017 Intrexon establishes CRADA with National Cancer Institute for the development of targeted cancer therapeutics in Solid tumours
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