Deudextromethorphan

Drug Profile

Deudextromethorphan

Alternative Names: AVP-786; CTP-786; d-DM; Deuterated dextromethorphan plus ultra low dose quinidine; Deuterated DM plus ultra low dose quinidine; Deuterated-dextromethorphan; Deuterated-DM

Latest Information Update: 14 Feb 2017

Price : $50

At a glance

  • Originator Concert Pharmaceuticals
  • Developer Avanir Pharmaceuticals
  • Class Antitussives; Morphinans; Opioid analgesics; Organic deuterium compounds; Small molecules
  • Mechanism of Action Cytochrome P 450 enzyme system inhibitors; KATP channel inhibitors; NMDA receptor antagonists; Norepinephrine plasma membrane transport protein inhibitors; Serotonin plasma membrane transport protein inhibitors; Sigma-1 receptor agonists; Sigma-1 receptor antagonists; Sodium channel antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Agitation
  • Phase II Major depressive disorder; Neurodegenerative disorders; Schizophrenia
  • Phase I Neuropathic pain
  • Preclinical Psychiatric disorders

Most Recent Events

  • 31 Mar 2017 Avanir Pharmaceuticals plans a phase II trial for Neurodegenerative disorders in USA (NCT03095066)
  • 14 Feb 2017 Chemical structure information added
  • 01 Dec 2015 Avanir initiates enrolment in a phase III trial for Agitation in patients with dementia of the Alzheimer's type (In adults, In the elderly) in USA (PO) (NCT02446132)
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