Drug Profile


Alternative Names: BB503; BBI 503; GB-503

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Boston Biomedical
  • Developer Boston Biomedical; Sumitomo Dainippon Pharma
  • Class Antineoplastics; Indoles; Pyrroles; Small molecules; Thiazoles
  • Mechanism of Action Cell death stimulants; Phosphotransferase inhibitors; Protein-serine-threonine kinase inhibitors; Stem cell inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cholangiocarcinoma; Gastrointestinal stromal tumours; Hepatocellular carcinoma; Ovarian cancer; Solid tumours

Most Recent Events

  • 13 Mar 2017 Phase-II clinical trials in Gastrointestinal stromal tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Recurrent) in Canada (PO) (NCT02232620)
  • 07 Jun 2016 Efficacy and adverse events data from a phase I trial in Solid tumours (Head and neck cancer) presented at the 52nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2016)
  • 15 Mar 2016 Biomarkers information updated
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