Drug Profile


Alternative Names: Nerve growth factor - Anabasis/Dompe; Oxervate; rhNGF; Sentinel

Latest Information Update: 25 May 2017

Price : $50

At a glance

  • Originator Anabasis Pharma
  • Developer Dompe Farmaceutici; Ospedale San Raffaele
  • Class Eye disorder therapies; Nerve growth factors; Neuroprotectants
  • Mechanism of Action Nerve growth factor receptor agonists; Neuron stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Keratitis; Retinitis pigmentosa
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Keratitis
  • Phase II Dry eyes; Retinitis pigmentosa
  • Phase I Glaucoma

Most Recent Events

  • 23 May 2017 CHMP recommends approval of Cenegermin for Neurotrophic keratitis in the EU
  • 11 Jan 2017 Dompé Farmaceutici plans a phase II trial for Dry eyes in USA (Ophthalmic) (NCT03019627)
  • 01 Jan 2017 Phase-II clinical trials in Dry eyes in USA (Ophthalmic) (NCT03019627)
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