Drug Profile


Alternative Names: Nerve growth factor - Anabasis/Dompe; Oxervate; rhNGF; Sentinel

Latest Information Update: 25 Sep 2017

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At a glance

  • Originator Anabasis Pharma
  • Developer Dompe Farmaceutici; Ospedale San Raffaele
  • Class Eye disorder therapies; Nerve growth factors; Neuroprotectants; Proteins
  • Mechanism of Action Nerve growth factor receptor agonists; Neuron stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Keratitis; Retinitis pigmentosa
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Keratitis
  • Phase II Dry eyes; Retinitis pigmentosa
  • Phase I Glaucoma

Most Recent Events

  • 20 Jul 2017 Preregistration for Keratitis in USA (Ophthalmic)
  • 20 Jul 2017 Registered for Keratitis in Liechtenstein, Norway, Iceland (Ophthalmic)
  • 20 Jul 2017 Registered for Keratitis in European Union (Ophthalmic)
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