Drug Profile


Alternative Names: 2140944; GSK 2140944; GSK-2140944E

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator GlaxoSmithKline
  • Class Acenaphthenes; Antibacterials; Aza compounds; Ketones; Piperidines; Pyridines; Pyrones; Small molecules
  • Mechanism of Action Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Gonorrhoea; Skin and soft tissue infections
  • Phase I Respiratory tract infections

Most Recent Events

  • 20 Jun 2017 GlaxoSmithKline completes a phase I pharmacokinetics trial in USA (IV) (NCT02729038)
  • 26 Oct 2016 Efficacy, adverse events and antimicrobial activity data from a phase II trial in Bacterial infections presented at IDWeek 2016 (IDW-2016)
  • 01 Aug 2016 GlaxoSmithKline initiates a phase I pharmacokinetics trial in Healthy volunteers in USA (PO, Tablet) (NCT02853435)
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