Research programme: eye disorder protein therapeutics - Eleven Biotherapeutics

Drug Profile

Research programme: eye disorder protein therapeutics - Eleven Biotherapeutics

Alternative Names: EBI-006; EBI-018; EBI-028; EBI-029; EBI-031

Latest Information Update: 06 Oct 2016

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At a glance

  • Originator Eleven Biotherapeutics
  • Class Proteins
  • Mechanism of Action Interleukin 1 receptor antagonists; Interleukin 17 receptor antagonists; Interleukin 6 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Diabetic macular oedema; Uveitis
  • Research Age-related macular degeneration; Ocular inflammation

Most Recent Events

  • 13 Sep 2016 Eleven Biotherapeutics withdraws a phase I trial prior to enrolment for Diabetic macular oedema in USA (NCT02842541)
  • 07 Jul 2016 US FDA approves IND application for EBI 031 in Diabetic macular oedema and uveitis (9201624; 9199120)
  • 14 Jun 2016 EBI 031 licensed to Roche in world
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