Drug Profile


Alternative Names: GS-4059; ONO-4059

Latest Information Update: 26 May 2017

Price : $50

At a glance

  • Originator Ono Pharmaceutical
  • Developer Gilead Sciences; Ono Pharmaceutical
  • Class Antineoplastics; Purines; Pyrrolidines; Small molecules
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic lymphocytic leukaemia; Sjogren's syndrome
  • Phase I B cell lymphoma; Rheumatoid arthritis
  • Preclinical Systemic lupus erythematosus

Most Recent Events

  • 21 Apr 2017 Chemical structure information added
  • 07 Apr 2017 Gilead Sciences plans a phase II trial for Sjogren's syndrome (Combination therapy) (NCT03100942)
  • 04 Apr 2017 Phase-II clinical trials in Sjogren's syndrome (Combination therapy, In adults, In the elderly) (PO) (NCT03100942)
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