Itacitinib

Drug Profile

Itacitinib

Alternative Names: INCB-039110; INCB39110

Latest Information Update: 24 Feb 2017

Price : $50

At a glance

  • Originator Incyte Corporation
  • Developer AstraZeneca; Incyte Corporation
  • Class Antineoplastics; Antipsoriatics; Antirheumatics; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Graft-versus-host disease; Hodgkin's disease; Non-small cell lung cancer
  • Phase I/II Non-Hodgkin's lymphoma; Pancreatic cancer; Solid tumours
  • Discontinued Myelofibrosis; Plaque psoriasis; Rheumatoid arthritis

Most Recent Events

  • 14 Feb 2017 Incyte Corporation plans global pivotal trials for Graft versus host disease
  • 01 Jan 2017 Incyte corporation completes a phase-II trial in Hodgkin's disease (Combination therapy, Second-line therapy or greater) in USA (PO) (NCT02456675)
  • 05 Dec 2016 Incyte Corporation terminates a phase-II clinical trial in Non-small cell lung cancer (Combination therapy) in USA (PO) (NCT02257619)
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