Drug Profile


Alternative Names: X-396

Latest Information Update: 20 Jan 2017

Price : $50

At a glance

  • Originator Xcovery
  • Developer Xcovery Holdings
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Non-small cell lung cancer
  • No development reported Haematological malignancies

Most Recent Events

  • 17 Jan 2017 Xcovery collaborates with NCI Formulary to co-develop ensartinib in Cancer
  • 07 Nov 2016 Betta Pharmaceuticals plans a phase I trial for Solid tumours (Late-stage disease) and Non-small cell lung cancer in China (PO) (NCT02959619)
  • 16 Sep 2016 Ludwig Institute for Cancer Research, MedImmune, Xcovery and Cancer Research Institute, New York plan a phase I/II trial for Non-small cell lung cancer (Metastatic disease, Monotherapy, Combination therapy) in USA (PO) (NCT02898116)
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