A 4250

Drug Profile

A 4250

Alternative Names: A-4250

Latest Information Update: 22 Feb 2017

Price : $50

At a glance

  • Originator Albireo
  • Developer Albireo Pharma
  • Class Antipruritics
  • Mechanism of Action Sodium-bile acid cotransporter-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Primary biliary cirrhosis; Intrahepatic cholestasis; Alagille syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Intrahepatic cholestasis; Primary biliary cirrhosis; Pruritus
  • Phase I Alagille syndrome

Most Recent Events

  • 15 Nov 2016 Albireo plans a pivotal phase III trial for Intrahepatic cholestasis in USA and European Union
  • 15 Oct 2016 Albireo terminates a phase-II clinical trial for Primary biliary cirrhosis and Cholestatic pruritus in Sweden (PO) (NCT02360852; EudraCT2014-004070-42)
  • 25 Jul 2016 Phase-II clinical trials in Intrahepatic cholestasis (PO) (Albireo pipeline, July 2016)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top