Research programme: G-protein-coupled bile acid receptor-1 agonists - ArdelyxAlternative Names: Gpbar1 Agonists - Ardelyx; RDX 009; RDX 98940; TGR5 Agonists - Ardelyx
Latest Information Update: 12 May 2016
At a glance
- Originator Ardelyx
- Class Small molecules
- Mechanism of Action GPBAR1 protein agonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
On Fast track
Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Diarrhoea; Inflammatory bowel diseases; Non-alcoholic steatohepatitis; Short bowel syndrome
- Discontinued Type 2 diabetes mellitus