Research programme: oncolytic viruses - Transgene

Drug Profile

Research programme: oncolytic viruses - Transgene

Alternative Names: anti-PD-1 immune checkpoint inhibitor - Transgene; J43-armed-Western Reserve oncolytic vaccinia virus; TG 6002; VV-TK-RR-FCU1; VVWR-TK-RR--Fcu1

Latest Information Update: 03 Oct 2017

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At a glance

  • Originator Transgene
  • Class Antibodies; Antineoplastics; Gene-directed enzyme-prodrug therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Checkpoint kinase inhibitors; Immunomodulators; PDCD 1 protein inhibitors; Prodrug activators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 03 Oct 2017 Assistance Publique plans the ONCOVIRAC phase I/II trial for Glioblastoma (Recurrent) in France (NCT03294486)
  • 13 Sep 2017 Transgene and The French National Cancer Institute plan a phase I trial for Glioblastoma
  • 17 May 2017 Pharmacodynamic data from a preclinical trial in Solid tumours presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
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