Research programme: oncolytic viruses - Transgene

Drug Profile

Research programme: oncolytic viruses - Transgene

Alternative Names: anti-PD-1 immune checkpoint inhibitor - Transgene; J43-armed-Western Reserve oncolytic vaccinia virus

Latest Information Update: 13 Apr 2017

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At a glance

  • Originator Transgene
  • Class Antibodies; Antineoplastics; Gene-directed enzyme-prodrug therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Checkpoint kinase inhibitors; Immunomodulators; PDCD 1 protein inhibitors; Prodrug activators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Solid tumours

Most Recent Events

  • 30 Mar 2017 Interim data from preclinical study in Solid tumours released by Transgene
  • 20 Mar 2017 Transgene files for patent protection for an oncolytic Vaccinia Virus expressing an anti-PD1 antibody in
  • 05 Sep 2016 Preclinical development is ongoing France
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