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Drug Profile

Lenrispodun - Intra-Cellular Therapies

Alternative Names: IC 200214-12; IC-200214; IC200214 phosphate; ITI 214; ITI-002; ITI-12-Cyclo-(S,R) phosphate; ITI-214 phosphate; ITI12-phosphate; ITI200214-phosphate; Lenrispodun phosphate

Latest Information Update: 29 Mar 2023

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At a glance

  • Originator Intra-Cellular Therapies
  • Class Aniline compounds; Antihypertensives; Antiparkinsonians; Cyclopentanes; Fluorinated hydrocarbons; Heart failure therapies; Imidazoles; Ketones; Nootropics; Pyrazoles; Pyridines; Small molecules
  • Mechanism of Action Adenosine A2B receptor modulators; Type 1 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Parkinson's disease
  • Phase I/II Heart failure
  • Preclinical Colorectal cancer; Hypertension
  • No development reported Cognition disorders

Most Recent Events

  • 13 Mar 2023 Phase-II clinical trials in Parkinson's disease (Adjunctive treatment) in USA (PO)
  • 01 Mar 2023 Intra-Cellular Therapies plans a phase II trial for Parkinson’s disease in March 2023
  • 08 Apr 2022 Pharmacodynamics data from preclinical trials in Breast cancer presented at American Association for Cancer Research (AACR-2022)

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