Research programme: chimeric antigen receptor-targeted therapies - Novartis/University of Pennsylvania

Drug Profile

Research programme: chimeric antigen receptor-targeted therapies - Novartis/University of Pennsylvania

Alternative Names: Adoptive T-cell immunotherapies - University of Pennsylvania/Novartis; CAR immunotherapies - University of Pennsylvania/Novartis

Latest Information Update: 26 Nov 2015

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At a glance

  • Originator University of Pennsylvania
  • Developer Novartis; University of Pennsylvania
  • Class CAR-T cell therapies; Gene therapies
  • Mechanism of Action Immunostimulants; T-cell receptor gene modulators; T-lymphocyte differentiation antigen modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 10 Oct 2014 Oxford BioMedica and Novartis enter into a process development and manufacturing collaboration for the LentiVector® technology, and tisagenlecleucel-T and other CAR T cell therapies
  • 31 Jul 2013 Life Technologies and Novartis enter a long-term supply and license agreement for Dynabead®CD3/CD28 CTS™ technology
  • 31 Jul 2013 Preclinical trials in Cancer in USA (Parenteral)
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