Drug Profile


Alternative Names: Hypoxin™; PR 610; Tarloxotinib bromide; TH-4000

Latest Information Update: 03 Aug 2017

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At a glance

  • Originator University of Auckland
  • Developer Proacta; Threshold Pharmaceuticals
  • Class Antineoplastics
  • Mechanism of Action Epidermal growth factor receptor antagonists; Protein tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Non-small cell lung cancer; Solid tumours; Squamous cell cancer

Most Recent Events

  • 03 Aug 2017 Chemical structure information added
  • 29 Jun 2017 Tarloxotinib is available for licensing as of 29 Jun 2017. http://www.thresholdpharm.com/overview-1/
  • 15 Dec 2016 Biomarkers information updated
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