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Pinometostat - Epizyme

Drug Profile

Pinometostat - Epizyme

Alternative Names: EPZ-5676

Latest Information Update: 22 Aug 2022

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At a glance

  • Originator Epizyme
  • Class Antineoplastics; Benzimidazoles; Cyclobutanes; Furans; Purines; Small molecules
  • Mechanism of Action DOT1L protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor cell lymphoblastic leukaemia-lymphoma; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acute biphenotypic leukaemia

Most Recent Events

  • 12 Aug 2022 Epizyme has been acquired by Ipsen
  • 02 Jan 2021 Celgene Corporation terminates its collaboration agreement with Epizyme for Pinometostat
  • 28 Apr 2020 No recent reports of development identified for phase-I development in Acute-biphenotypic-leukaemia(In adolescents, In children, In infants) in Canada (IV, Infusion)
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