Drug Profile


Alternative Names: SP 333

Latest Information Update: 06 Jun 2016

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At a glance

  • Originator Synergy Pharmaceuticals Inc
  • Class Anti-inflammatories; Peptide hormones
  • Mechanism of Action Guanylate cyclase C agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Constipation
  • Phase I Ulcerative colitis

Most Recent Events

  • 16 Feb 2016 Phase II development for Constipation is ongoing in USA (PO) (Synergy Pipeline, February 2016)
  • 18 Dec 2014 Synergy Pharmaceuticals completes a phase II trial in Constipation in USA
  • 19 Nov 2014 Phase-I clinical trials in Ulcerative colitis in USA (PO)
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