Drug Profile


Alternative Names: AR-12286/travoprost; PG-286; Travoprost/AR-12286; Verosudil/travoprost

Latest Information Update: 27 Sep 2013

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At a glance

  • Originator Aerie Pharmaceuticals
  • Class Acetamides; Antiglaucomas; Antihypertensives; Isoquinolines; Prostaglandins; Small molecules; Thiophenes
  • Mechanism of Action Prostaglandin F2 alpha agonists; Rho-associated kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Glaucoma; Ocular hypertension

Most Recent Events

  • 30 Jun 2013 Discontinued - Phase-II for Glaucoma in USA (Ophthalmic)
  • 30 Jun 2013 Discontinued - Phase-II for Ocular hypertension in USA (Ophthalmic)
  • 27 Feb 2013 Aerie Pharmaceuticals initiates enrolment in a phase IIb trial for Glaucoma or Ocular hypertension in USA (NCT01789736)
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