Netarsudil mesylate

Drug Profile

Netarsudil mesylate

Alternative Names: AR-13224; AR13324; Rhopressa

Latest Information Update: 29 Dec 2016

Price : $50

At a glance

  • Originator Duke University Medical Center
  • Developer Aerie Pharmaceuticals
  • Class Antiglaucomas; Small molecules
  • Mechanism of Action Connective tissue growth factor inhibitors; Norepinephrine plasma membrane transport protein inhibitors; Rho-associated kinase inhibitors; Transforming growth factor beta type II receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Glaucoma; Ocular hypertension
  • Preclinical Neurological disorders

Most Recent Events

  • 23 Dec 2016 Aerie Pharmaceuticals plans to resubmit NDA to the US FDA for Netarsudil mesylate for Glaucoma and Ocular hypertension, at the end of the first quarter of 2017
  • 02 Nov 2016 Aerie Pharmaceutical completes a phase II trial in Glaucoma and Ocular hypertension in USA (NCT02874846)
  • 27 Oct 2016 Regulatory submission withdrawn for Glaucoma in USA (Ophthalmic)
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