VAY 736

Drug Profile

VAY 736

Alternative Names: NOV-5; VAY-736

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator MorphoSys; Novartis
  • Developer H. Lee Moffitt Cancer Center and Research Institute; MorphoSys; Novartis
  • Class Antineoplastics; Antirheumatics; Monoclonal antibodies; Neuropsychotherapeutics; Skin disorder therapies
  • Mechanism of Action B-cell activation factor receptor modulators; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple sclerosis; Pemphigus vulgaris; Rheumatoid arthritis; Sjogren's syndrome
  • No development reported Chronic lymphocytic leukaemia

Most Recent Events

  • 23 Sep 2017 Novartis plans a phase II trial for Idiopathic pulmonary fibrosis (NCT03287414)
  • 12 Jul 2017 Novartis Pharmaceuticals plans the phase II/III AMBER trial in Autoimmune hepatitis (NCT03217422; EudraCT2017-001555-32)
  • 27 Jun 2017 Phase-II clinical trials in Sjogren's syndrome in Germany, Japan, Spain, Portugal, Hungary, Austria (SC) (EudraCT2016-003292-22) (NCT02962895)
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