IMO 8400

Drug Profile

IMO 8400

Alternative Names: IMO-8400

Latest Information Update: 11 Jan 2017

Price : $50

At a glance

  • Originator Idera Pharmaceuticals
  • Class Antisense oligonucleotides; Immunotherapies
  • Mechanism of Action Toll-like receptor 7 antagonists; Toll-like receptor 8 antagonists; Toll-like receptor 9 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Diffuse large B cell lymphoma; Waldenstrom's macroglobulinaemia
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Dermatomyositis
  • Suspended Diffuse large B cell lymphoma; Waldenstrom's macroglobulinaemia
  • No development reported Graft-versus-host disease; Systemic lupus erythematosus
  • Discontinued Duchenne muscular dystrophy; Plaque psoriasis

Most Recent Events

  • 26 Sep 2016 Suspended - Phase-I/II for Diffuse large B cell lymphoma (Second-line therapy or greater) in USA (SC)
  • 26 Sep 2016 Suspended - Phase-I/II for Waldenstrom's macroglobulinaemia (Second-line therapy or greater) in USA (SC)
  • 23 Mar 2016 Idera Pharmaceuticals terminates a planned phase II trial in Duchenne muscular dystrophy in USA
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