Drug Profile


Alternative Names: Hafnium Oxide nanoparticles; NBTX 3; NBTXR-3; PEP-503

Latest Information Update: 25 May 2017

Price : $50

At a glance

  • Originator Nanobiotix
  • Developer Nanobiotix; PharmaEngine
  • Class Antineoplastics; Radiosensitisers
  • Mechanism of Action Free radical stimulants; Radiography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Solid tumours

Highest Development Phases

  • Phase II/III Soft tissue sarcoma
  • Phase I/II Head and neck cancer; Prostate cancer; Rectal cancer
  • Preclinical Hepatocellular carcinoma; Solid tumours

Most Recent Events

  • 01 Apr 2017 NBTXR 3 is still in preclinical development for Solid tumours in USA
  • 23 Mar 2017 The Independent Data Monitoring Committee recommends the continuation of enrolment in the phase III trial on Soft tissue sarcoma
  • 14 Dec 2016 Preliminary efficacy and adverse events data from a phase I/II trial in Hepatocellular carcinoma released by Nanobiotix
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