Drug Profile


Alternative Names: Hafnium Oxide nanoparticles; NBTX 3; NBTXR-3; PEP-503

Latest Information Update: 03 Nov 2017

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At a glance

  • Originator Nanobiotix
  • Developer Nanobiotix; PharmaEngine
  • Class Antineoplastics; Radiosensitisers
  • Mechanism of Action Free radical stimulants; Radiography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Solid tumours

Highest Development Phases

  • Phase II/III Soft tissue sarcoma
  • Phase I/II Head and neck cancer; Prostate cancer; Rectal cancer
  • Preclinical Hepatocellular carcinoma; Solid tumours

Most Recent Events

  • 09 Nov 2017 IND approval for phase I trial in Head and neck and Lung cancer expected in 1H 2018
  • 31 Oct 2017 Nanobiotix plans a clinical trial for Cancer (Combination therapy) in USA
  • 23 Oct 2017 NanoBiotix completes patient enrolment in a phase II/III trial in Soft tissue sarcoma in Australia, Belgium, France, Germany, Hong Kong, Hungary, Italy, Norway, the Philippines, Poland, Romania, South Africa and Spain
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