Research programme: antisense therapies - AstraZeneca/Ionis Pharmaceuticals

Drug Profile

Research programme: antisense therapies - AstraZeneca/Ionis Pharmaceuticals

Alternative Names: AZD-4785; AZD8233; IONIS-AZ4-2.5-LRx; IONIS-KRAS-2.5Rx

Latest Information Update: 30 Dec 2016

Price : $50

At a glance

  • Originator Isis Pharmaceuticals
  • Developer AstraZeneca; Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer; Cardiovascular disorders
  • Research Kidney disorders; Metabolic disorders

Most Recent Events

  • 19 Dec 2016 Preclinical trials in Cardiovascular disorders in USA (unspecified route)
  • 16 Dec 2016 Preclinical trials in Cancer in USA (Parenteral)
  • 18 Dec 2015 Isis Pharmaceuticals is now called Ionis Pharmaceuticals
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top