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Iberdomide - Bristol Myers Squibb

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Drug Profile

Iberdomide - Bristol Myers Squibb

Alternative Names: BMS-986382; CC-220; IBER; Iberdomide hydrochloride

Latest Information Update: 21 Mar 2024

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At a glance

  • Originator Celgene Corporation
  • Developer Bristol-Myers Squibb; Celgene Corporation; Hackensack Meridian Health
  • Class Anti-inflammatories; Antineoplastics; Isoindoles; Piperidones; Skin disorder therapies; Small molecules
  • Mechanism of Action Ubiquitin protein ligase complex modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Multiple myeloma
  • Phase II Atopic dermatitis; Systemic lupus erythematosus
  • Phase I B-cell lymphoma; Follicular lymphoma; Renal failure
  • No development reported Non-Hodgkin's lymphoma
  • Discontinued Cutaneous lupus erythematosus; Haematological malignancies; Sarcoidosis; Systemic scleroderma

Most Recent Events

  • 12 Mar 2024 Hackensack Meridian Health suspends a Phase-I/II clinical trials in Multiple myeloma (Combination therapy, First-line therapy) in USA (PO) due to serious adverse event which is under review (NCT05199311)
  • 20 Feb 2024 Pfizer initiates the phase I MagnetisMM-4 trial for Multiple myeloma (Combination therapy, Second-line therapy or greater) in Canada (PO) (NCT06215118)
  • 25 Jan 2024 Bristol-Myers Squibb plans a phase III trial in Multiple myeloma (Combination therapy) in Germany (PO) (NCT06216158)
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