TGR 1202

Drug Profile

TGR 1202

Alternative Names: RP 5307; RP-5264; TGR-1202

Latest Information Update: 09 Jun 2017

Price : $50

At a glance

  • Originator Incozen Therapeutics; Rhizen Pharmaceuticals
  • Developer Columbia University Medical Center; TG Therapeutics Inc; Vanderbilt-Ingram Cancer Center
  • Class Antineoplastics; Benzopyrans; Pyrazoles; Pyrimidines; Small molecules
  • Mechanism of Action Casein kinase Iepsilon inhibitors; Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Diffuse large B cell lymphoma; Chronic lymphocytic leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Chronic lymphocytic leukaemia
  • Phase II Diffuse large B cell lymphoma; Follicular lymphoma
  • Phase I/II Lymphoma
  • Phase I Hodgkin's disease; Mantle-cell lymphoma; Myelofibrosis; Non-Hodgkin's lymphoma; Polycythaemia vera; Solid tumours
  • No development reported Haematological malignancies

Most Recent Events

  • 07 Jun 2017 Phase-II clinical trials in Follicular lymphoma (Second-line therapy or greater, Refractory metastatic disease) in USA (PO) before June 2017 (NCT03178201)
  • 06 Dec 2016 Phase-I clinical trials in Diffuse large B cell lymphoma (Late-stage disease, Combination therapy, In the elderly) in USA prior to December 2016 (PO)
  • 06 Dec 2016 Phase-I clinical trials in Follicular lymphoma (Combination therapy, In the elderly, Late-stage disease) in USA (PO)
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