Drug Profile


Alternative Names: REGN-1500

Latest Information Update: 03 Oct 2017

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At a glance

  • Originator Regeneron Pharmaceuticals; Sanofi
  • Developer Regeneron Pharmaceuticals
  • Class Antihyperlipidaemics; Monoclonal antibodies
  • Mechanism of Action ANGPTL3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hyperlipoproteinaemia type IIa

Most Recent Events

  • 26 Aug 2017 Updated efficacy and adverse events data from a phase II trial in Hyperlipoproteinaemia type IIa presented at the Annual Congress of the European Society of Cardiology (ESC-2017)
  • 08 Jun 2017 Regeneron Pharmaceuticals plans a phase II trial for Hypercholesterolaemia (NCT03175367)
  • 24 May 2017 Pharmacodynamics data from preclinical study in Atherosclerosis released by Regeneron Pharmaceuticals
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