Drug Profile


Alternative Names: ABT-494

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Abbott Laboratories
  • Developer AbbVie
  • Class Antirheumatics; Fluorocarbons; Imidazoles; Pyrazines; Pyrroles; Pyrrolidines
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase 3 inhibitors; Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Rheumatoid arthritis; Ulcerative colitis
  • Phase II Atopic dermatitis; Crohn's disease

Most Recent Events

  • 28 Dec 2016 Phase-III clinical trials in Rheumatoid arthritis (Treatment-experienced) in Spain (PO) (EudraCT2016-000933-37)
  • 06 Dec 2016 Phase-III clinical trials in Rheumatoid arthritis (Treatment-experienced) in Latvia (PO) (EudraCT2016-000933-37)
  • 24 Nov 2016 Phase-III clinical trials in Rheumatoid arthritis (Treatment-experienced) in Hungary (PO, Tablet) (EudraCT2016-000933-37)
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