Drug Profile


Alternative Names: ABT-494

Latest Information Update: 21 Jun 2017

Price : $50

At a glance

  • Originator Abbott Laboratories
  • Developer AbbVie
  • Class Antirheumatics; Fluorocarbons; Imidazoles; Pyrazines; Pyrroles; Pyrrolidines
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase 3 inhibitors; Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Psoriatic arthritis; Rheumatoid arthritis; Ulcerative colitis
  • Phase II Atopic dermatitis; Crohn's disease

Most Recent Events

  • 09 Jun 2017 AbbVie plans a phase IIb/III trial for Ankylosing spondylitis in USA (NCT03178487)
  • 07 Jun 2017 Safety and efficacy data from the phase III SELECT-NEXT trial in Rheumatoid Arthritis released by AbbVie
  • 09 May 2017 Phase-III clinical trials in Rheumatoid arthritis (Treatment-experienced) in Canada, Hungary, Germany, Latvia, Portugal, Belgium, Spain (PO) (EudraCT2016-000933-37; NCT03086343)
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