Drug Profile


Alternative Names: ATM-AVI; Aztreonam-avibactam; PF 06947387

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator AstraZeneca
  • Class Amides; Antibacterials; Heterocyclic bicyclo compounds; Monobactams; Small molecules; Sulfates
  • Mechanism of Action Beta lactamase inhibitors; Cell wall inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Intra-abdominal infections
  • Phase I Gram-negative infections

Most Recent Events

  • 07 Nov 2017 Pfizer plans a phase III trial for Gram-negative infections in March 2018 (NCT03329092)
  • 06 Jul 2017 Chemical structure information added
  • 24 Aug 2016 AstraZeneca plans to sell the commercialisation and development rights to late-stage small molecule antibiotics to Pfizer
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