Mesenchymal stem cell therapy (HepaStem) - Promethera Biosciences

Drug Profile

Mesenchymal stem cell therapy (HepaStem) - Promethera Biosciences

Alternative Names: hALDMSC - Promethera; HepaStem; Heterologous Human Adult Liver derived Progenitor Cells; HHALPC; human Adult Liver-Derived Mesenchymal Progenitor/Stem Cells - Promethera

Latest Information Update: 09 Oct 2017

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At a glance

  • Originator Catholic University of Louvain
  • Developer Promethera Biosciences
  • Class Antineoplastics; Stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Inborn urea cycle disorders; Liver disorders
  • New Molecular Entity No

Highest Development Phases

  • Phase II Inborn urea cycle disorders; Liver failure
  • Phase I/II Liver disorders
  • Preclinical Non-alcoholic steatohepatitis
  • Research Haemophilia; Hepatic fibrosis
  • No development reported Glycogen storage disease type I; Phenylketonuria

Most Recent Events

  • 05 Oct 2017 Promethera Biosciences and Shibuya enter into collaboration to develop manufacturing platform for stem cell therapies for treatment of liver disorders
  • 09 Jan 2017 Promethera Biosciences and LifeLiver enter into a strategic alliance to jointly develop HepaStem in South Korea
  • 14 Nov 2016 Pharmacodynamics data from a preclinical studies in Non-alcoholic steatohepatitis released by Promethera Biosciences
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