Esketamine - Johnson & Johnson

Drug Profile

Esketamine - Johnson & Johnson

Alternative Names: JNJ-54135419; S-ketamine

Latest Information Update: 11 Oct 2017

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At a glance

  • Originator Johnson & Johnson
  • Class Analgesics; Antidepressants; Chlorobenzenes; Cyclohexanones; General anaesthetics; Small molecules
  • Mechanism of Action NMDA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Major depressive disorder

Most Recent Events

  • 04 Oct 2017 Janssen Research & Development plans a phase I trial in Healthy volunteers in Belgium (NCT03298906)
  • 10 Aug 2017 Janssen completes the phase III TRANSFORM-3 trial in Major depressive disorder (Treatment-resistant, Adjuvant therapy) in United Kingdom, Spain, South Africa, Poland, Lithuania, France, Finland, Bulgaria, Brazil, Belgium, USA, Sweden (Intranasal) (NCT02422186)
  • 15 Jun 2017 Phase-III clinical trials in Major depressive disorder (Adjunctive treatment) in USA, Argentina, Austria, Belgium, Brazil, Canada, Czech Republic, France, Lithuania, Poland, Turkey, United Kingdom (Intranasal) (NCT03097133)
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