Drug Profile


Alternative Names: IgG-degrading enzyme of Streptococcus pyogenes; IgG-endopeptidase; Mac-1; Streptococcal cysteine proteinase

Latest Information Update: 02 Jan 2017

Price : $50

At a glance

  • Originator Hansa Medical AB
  • Developer Hansa Medical AB; University College London
  • Class Bacterial proteins; Enzymes
  • Mechanism of Action Immunoglobulin modulators; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Transplant rejection
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Thrombotic thrombocytopenic purpura; Transplant rejection
  • Discontinued Rheumatoid arthritis; Streptococcal infections

Most Recent Events

  • 22 Dec 2016 Hansa Medical terminates a phase II trial in Thrombotic thrombocytopenic purpura in United Kingdom
  • 21 Dec 2016 Hansa Medical completes a phase II trial in Transplant rejection (Prevention) in Sweden
  • 11 Oct 2016 Phase-II clinical trials in Thrombotic thrombocytopenic purpura in United Kingdom (IV)
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