Osimertinib

Drug Profile

Osimertinib

Alternative Names: AZD-9291; Mereletinib; TAGRISSO

Latest Information Update: 09 Aug 2017

$50 / €47 *
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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; Eli Lilly; European Thoracic Oncology Platform; Incyte Corporation; Kyushu University; National Cancer Institute (USA); National University Hospital (Singapore); Singapore Clinical Research Institute
  • Class Acrylamides; Aniline compounds; Antineoplastics; Dimethylamines; Indoles; Pyrimidines; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists; Protein tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Non-small cell lung cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Non-small cell lung cancer
  • Phase II Carcinomatous meningitis
  • Phase I Solid tumours

Most Recent Events

  • 08 Aug 2017 AstraZeneca plans a phase II trial for Non-small cell lung cancer(Metastatic disease, Late-stage disease) (NCT03239340)
  • 11 Jul 2017 AstraZeneca completes AURA2 and AURA phase II trials in Non-small cell lung cancer (Second-line therapy or greater, Late-stage disease) in USA, Canada, Hong Kong, Italy, Japan, South Korea, Spain and Taiwan (AstraZeneca pipeline, July 2017)
  • 11 Jul 2017 AstraZeneca completes the phase III AURA3 trial for Non-small cell lung cancer (Late-stage disease, Second-line therapy or greater) in USA, Australia, Canada, Hong Kong, Italy, Taiwan, Sweden, Germany, Japan, South Korea, Spain, Russia, the Netherlands, China, France, Hungary, Mexico and United Kingdom (AstraZeneca pipeline, July 2017)
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