CK 2127107

Drug Profile

CK 2127107

Alternative Names: CK-107; CK-2127107

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Cytokinetics
  • Developer Astellas Pharma; Cytokinetics
  • Class Small molecules
  • Mechanism of Action Troponin tropomyosin complex stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal muscular atrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Chronic obstructive pulmonary disease; Spinal muscular atrophy
  • Phase I Muscle fatigue
  • No development reported Muscular atrophy

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Muscle-wasting(In volunteers) in USA (PO, Tablet)
  • 27 Jul 2017 Phase-II clinical trials in Amyotrophic lateral sclerosis in Canada (PO) (NCT03160898)
  • 27 Jul 2017 Cytokinetics and Astellas Pharma initiate the phase II FORTITUDE-ALS trial in Amyotrophic lateral sclerosis in USA (PO) (NCT03160898)
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