CJM 112

Drug Profile

CJM 112

Alternative Names: CJM112

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Novartis
  • Class Antineoplastics; Antipsoriatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action IL17A protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acne; Hidradenitis suppurativa
  • Phase I/II Plaque psoriasis
  • Phase I Multiple myeloma; Solid tumours
  • Preclinical Multiple sclerosis

Most Recent Events

  • 03 Oct 2017 Novartis Pharmaceuticals plans a phase II trial for moderate to severe Asthma (Adjunctive treatment, In adults) (NCT03299686)
  • 14 Aug 2017 Phase-I clinical trials in Multiple myeloma (Second-line therapy or greater) in Switzerland, Canada (unspecified route) (NCT03111992)
  • 22 Mar 2017 Novartis plans a phase I trial of CJM 112 alone and of CJM 112 or LCL 161 in combination with PDR 001 for Multiple myeloma (Second-line therapy) (NCT03111992)
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