Doxorubicin encapsulated nanocells - EnGeneIC

Drug Profile

Doxorubicin encapsulated nanocells - EnGeneIC

Alternative Names: EGFREDVDox; Doxorubicin packaged EDV™ nanocells - EnGeneIC; Doxorubicin-loaded EDV nanocells; EGFR(V)-EDV-Dox; EnGeneIC Delivery Vehicle™; EnGeneIC Dream Vector™; VEDVDox

Latest Information Update: 09 Aug 2017

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At a glance

  • Originator EnGeneIC
  • Class Anthracyclines; Cytostatic antibiotics; Doxorubicins; Small molecules
  • Mechanism of Action Immunostimulants; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Glioblastoma
  • Phase I Solid tumours
  • Preclinical Brain cancer

Most Recent Events

  • 09 Aug 2017 Phase-I clinical trials in Solid tumours (Treatment-naive) in Australia (IV) (EnGeneIC pipeline, August 2017)
  • 02 Mar 2017 Doxorubicin encapsulated nanocells receives Orphan Drug status for Glioblastoma in USA
  • 25 Oct 2016 Phase-I clinical trials in Glioblastoma (Recurrent, Late-stage disease, Second-line therapy or greater) in USA (IV) (NCT02766699)
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