AZD 2811

Drug Profile

AZD 2811

Alternative Names: AZD 1152 hQPA; AZD2811

Latest Information Update: 21 Sep 2017

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At a glance

  • Originator AstraZeneca; BIND Therapeutics
  • Developer AstraZeneca; Pfizer
  • Class Acetamides; Antineoplastics; Fluorobenzenes; Pyrazoles; Quinazolines
  • Mechanism of Action Aurora kinase B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes
  • Phase I Solid tumours
  • Preclinical Diffuse large B cell lymphoma; Lung cancer

Most Recent Events

  • 31 Jul 2017 Phase-I/II clinical trials in Myelodysplastic syndromes and Acute myeloid leukaemia (Second-line therapy or greater, Treatment-naive) in USA (IV) (NCT03217838)
  • 13 Jul 2017 AstraZeneca plans a phase I/II trial for Acute myeloid leukaemia and Myelodysplastic syndromes (Second-line therapy or greater, Treatment-naive) (IV) (NCT03217838)
  • 01 Apr 2017 Pharmacodynamics data from preclinical studies in Cancer presented at the 108th Annual Meeting of the American Association of Cancer (AACR-2017)
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