Andecaliximab

Drug Profile

Andecaliximab

Alternative Names: GS 5745; MMP9 mAb inhibitor - Gilead

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Gilead Sciences
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Matrix metalloproteinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Gastric cancer
  • Phase II/III Ulcerative colitis
  • Phase II Crohn's disease; Cystic fibrosis; Rheumatoid arthritis
  • Phase I Chronic obstructive pulmonary disease; Solid tumours

Most Recent Events

  • 07 Mar 2017 GS 5745 is now called andecaliximab (NCT01803282)
  • 27 Feb 2017 Andecaliximab is still in phase I trials for Solid tumours in USA (Gilead Sciences 10-K, February 2017)
  • 01 Dec 2016 Gilead Sciences completes A Phase II trial in Crohn's disease in US, Australia, Canada, New Zealand, Hungary, Germany, Czech Republic, Spain, the UK, France, Italy, Iceland, Poland and South Africa (EudraCT2015-001249-10; NCT02405442)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top