GS 5745

Drug Profile

GS 5745

Alternative Names: GS-5745; MMP9 mAb inhibitor - Gilead

Latest Information Update: 19 Jan 2017

Price : $50

At a glance

  • Originator Gilead Sciences
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Matrix metalloproteinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Gastric cancer
  • Phase II/III Ulcerative colitis
  • Phase II Crohn's disease; Cystic fibrosis; Rheumatoid arthritis
  • Phase I Chronic obstructive pulmonary disease
  • No development reported Solid tumours

Most Recent Events

  • 01 Dec 2016 Gilead Sciences completes A Phase II trial in Crohn's disease in US, Australia, Canada, New Zealand, Hungary, Germany, Czech Republic, Spain, the UK, France, Italy, Iceland, Poland and South Africa (EudraCT2015-001249-10; NCT02405442)
  • 09 Nov 2016 Phase-II clinical trials in Rheumatoid arthritis (Adjunctive treatment) in USA, Australia, Germany, Hungary, Mexico, Taiwan and Belgium (SC) (Gilead Sciences pipeline, November 2016)
  • 01 Nov 2016 Phase-II clinical trials in Cystic fibrosis (Adjunctive treatment) in Australia, Canada, France, Ireland (SC) (NCT02759562)
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