Lumicitabine - Alios BioPharma/Janssen

Drug Profile

Lumicitabine - Alios BioPharma/Janssen

Alternative Names: AL 8176; ALS 008176; ALS-8176; JNJ-1575; JNJ-64041575

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Alios BioPharma
  • Developer Alios BioPharma; Janssen Research & Development
  • Class Antivirals; Furans; Nucleosides; Pyrimidines
  • Mechanism of Action RNA replicase inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Respiratory syncytial virus infections
  • Preclinical Metapneumovirus infections; Parainfluenza virus infections

Most Recent Events

  • 09 Nov 2017 Janssen Research & Development plans a phase II follow-up trial for Respiratory syncytial virus infections (In infants, In children) in USA, Australia, Belgium, Brazil, Canada, Chile, Colombia, Czech Republic, Finland, France, Germany, Ireland, Israel, Japan, South Korea, Malaysia, New Zealand, Panama, Portugal, Slovakia, Spain, Sweden, Taiwan, Thailand, Ukraine and United Kingdom in November 2017 (NCT03332459)
  • 28 Jun 2017 Janssen initiates enrolment in a phase I pharmacokinetic trial in Germany (NCT03189498)
  • 21 Jun 2017 Janssen plans a pharmacokinetic phase I trial in Germany (NCT03189498)
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