AB 16B5

Drug Profile

AB 16B5

Alternative Names: 16B5; AB-16B5; AB-sCLU mAB; Anti-clusterin monoclonal antibody - Alethia Biotherapeutics

Latest Information Update: 06 Jul 2017

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At a glance

  • Originator National Research Council Biotechnology Research Institute
  • Developer Alethia BioTherapeutics
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Clusterin inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 04 Apr 2017 Adverse events, efficacy and pharmacokinetics data from the phase I trial in solid tumours presented at the 108th annual meeting of the American Association for Cancer Research (AACR-2017)
  • 21 May 2015 Alethia Biotherapeutics is planning a phase I trial in Solid tumours (Late-stage disease) in Canada (NCT02412462)
  • 01 Apr 2015 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in Canada (IV) (NCT02412462)
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